This joint foundation formula works very well to help maintain equine joint mobility, strong bones, cartilage, structural integrity and function by reducing free radical formation and oxidative stress. MSM is important for connective tissue integrity and helps maintain normal, healthy cartilage. Glucosamine may stimulate the production of proteoglycans, which helps maintain the health and resiliency of joints and connective tissue and helps maintain synovial fluid that lubricates the joint.